Part 2: Health apps, wearables, and sensors: The advancing frontier of digital health

单词effective 联想记忆:
Bored with your day-to-day life? It’s time to go on an adventure and refresh yourself! The Antarctic is undoubtedly a good choice. Watching native penguins playing and seeing millions of seabirds flying across the sky is much more exciting than watching TV documentaries. Imagine how cool and fascinating it is to be in a world of majestic icebergs and unexplored mountain ranges. But remember, it’s a polar region, so prepare well before you set off. Insulated boots, warm coats, gloves, wool socks and hats are a must.
4.你的同事会泄密。
During the summers, Good Humor ice cream trucks visit the company's campuses every other Friday during lunchtime. In the fall, cider and doughnuts are served twice a month, mid-morning.
suc下面,cumb躺-躺下去-屈从
该剧在今年暑期播出,受众的是喜欢奇幻浪漫题材的年轻观众。
Nearly all the entrepreneurs (93 per cent) rated their new skills as important or very important in their decision. “I understand the value of my skills without the ‘fear’ of not being employed,” said one.
Though she says 'women have a tight to be angry', McGowan says #MeToo activists have 'sold themselves a fiction' rather than face up to the true nature of Hollywood.
但是,当今年12月WTO成员国聚集在布宜诺斯艾利斯召开两年一度的部长级会议时,我们将一尝世界新秩序的味道。一如既往的是,目前尚不清楚WTO此次能否产生一些实质性内容。但真正的考验在于,WTO有史以来第一次不由美国牵头讨论。中国或欧盟会取而代之吗?印度会像过去一样一心阻挠任何协议吗?
詹妮弗·劳伦斯也凭借她在《奋斗的乔伊》中的表演喜获最佳女主角奖项。
The Asia-Pacific is the common home of all countries in the region. China does not want to see any party in the Asia-Pacific region feel compelled to choose sides under the influence of a Cold-War mentality.
另一方面,世界杯作为体育盛事和文化体验也成为了热门搜索项。
1.Rain Man
A devastating financial crisis led business owners and corporate executives to be especially wary about adding staff or investing in new equipment. Some worry about risks from Washington or overseas. Others are seeing consumers maintain their slow-but-steady spending, providing little incentive to deploy their cash stockpiles.
He failed to do so and Presti smartly moved on while he could still recoup some value.
The Disaster Artist is part buddy movie, part show-business fable, and part behind-the-scenes DVD featurette.
However, you know when your cycles are over when the washer and dryer stop making noise. And you know when the weather is ugly by simply looking outside, or checking your weather app. Therefore, the product is basically just another way hackers can get into your home.
的确,所有的托管公司都提供了一个基本的CMS系统(内容管理系统),但它们是否具有足够的灵活性,确保你的顾客能在网络上找到你?大概不能。WordPress是一个开源的CMS系统,你还可以选择定制或持续优化。你可能需要某个有开发经验的人帮你安装,但一旦安装完毕,你八成不需要任何帮助就能自己发布内容了。
总部位于广东的房地产开发企业碧桂园集团现年35岁的女继承人杨惠妍以485亿元的身家紧随其后。
Enrollment: 503
Apple (AAPL, Fortune 500) announced that it would put $30 billion of its cash toward share repurchases. The news made investors happy: The stock popped, and even a week later was up 12% relative to the S&P over that same 7-day period. The buybacks were part of a larger $130 billion capital return program that the company said would extend through 2015.
File this under "great, yet stupid gift ideas." The BOx bottle opener claims to be the "world's first smart bottle opener" but it's not groundbreaking. This bottle opener sends a message to your friends via Messenger every time you open a bottle — crazy, right?
威廉姆斯认为,这些影响也将波及到一些大宗商品净进口国,大宗商品价格上涨可能提高资源密集型制成品(如钢铁)的价格,提振韩国等国的出口产品价值。
房地产经纪公司莱坊(Knight Frank)的数据显示,今年第一季度,香港豪宅租金同比下跌5.2%,跌幅超过内罗毕以外的任何其他城市。就在去年9月价格下跌之后,运动品牌阿迪达斯(Adidas)在香港租入了一间1.3万平方英尺的店铺,租金相比上一个租户、配饰品牌蔻驰(Coach)低了22%。
而分子马达将会为医药和能源领域带来巨大的潜力。


德文·韦德
科学家们让夫妻进入实验室,在他们开始“别扭”对话时观察他们的压力水平。研究发现,面对压力时,用大笑等积极情绪缓解压力的夫妻在一起的时间往往更久。
你的老板有望学会使用Twitter


With the increasing proliferation and sophistication of mobile phones, wearable devices such as smart watches, and sensors that can measure and gather a variety of data, public interest is growing in using consumer electronics to take ownership of personal health and wellness. A 2015 survey found that 66% of Americans age 66 and older want to use mobile technologies to improve their health by receiving medication reminders and tracking diet and nutrition, physical activity, and symptoms.[1

The statement said: "We sincerely apologize to Moonlight, La La Land, Warren Beatty, Faye Dunaway, and Oscar viewers for the error that was made during the award announcement for Best Picture."
“Airbnb is here to stay,” Mr. Gottsegen said. “Instead of fighting it, we should wrap our arms around it and make it better.”
Oops. Better luck in 2015, everybody.
A Method to the Madness

Health apps and wearables
Health apps and wearables can unobtrusively gauge physiological and emotional states and collect, quantify, and monitor data regarding a user’s day-to-day behaviors. This “quantified self” can increase users’ self-awareness regarding their behavior and encourage positive changes to their overall health and well-being.[2] These commercially available devices also integrate an array of features to provide motivation through reward systems, opportunities for social in-teraction, tools for self-improvement, and prompts. The novelty, affordability, practicality, and ease of use have resulted in increased consumer enthusiasm and the pervasiveness of these devices.[3,4] With this growing interest in personal health, members of the general public are becoming more involved in monitoring and improving their own health habits.[5-10

Undoubtedly, merely tracking data through a device is not enough to maintain good health-related behaviors long-term, and the software must also incorporate motivational constructs important for the adoption and habituation of behaviors. For instance, a systematic review of studies that considered the use of electronic activity monitor systems found short-term changes in physical activity with self-monitoring, but no demonstration of superiority when the systems were compared with other interventions.[11] Another review of studies on the viability of using mobile technology for measuring and influencing physical activity found that most apps allow users to document their activity, set goals, review real-time feedback, connect to a social support network, and access online expertise.[12] However, less common among these apps were prompts to act and opportunities for problem solving and action planning, which are crucial constructs that translate intention into long-term behavior change.[13]

Sensor technologies
Sensor technologies have begun to enter the telehealth landscape and are primarily focused on continuous monitoring and precise diagnostics to inform management of various health conditions and diseases.[14-17] Sensors can be integrated into a watch or arm band or adhesive bandages and clothing, and then programmed to collect data on cardiac rhythm, heart rate, blood pressure, respiration, oxygen saturation, galvanic skin response, glucose levels, body temperature, body motions, ambient temperature, and global positioning. For health care providers, sensor inputs can permit remote monitoring, real-time teleconferencing, and timely care for patients with chronic diseases. For both patients and clinicians, telehealth supported by sensors can have profound implications. Clinicians can provide timely and patient-centred care to those living at a distance with chronic disease and can coordinate care when multiple providers are involved, reducing costs to the health care system.

A current clinical example is the management of paroxysmal atrial fibrillation with a mobile ECG and app that monitors the patient’s electrical rhythm to detect frequency and patterns of arrhythmias, and may even allow patients to share ultrasound and electrocardiogram data with their health care provider.[18-20] Telemonitoring with sensors can also support self-management of chronic diseases and detect early signs of deterioration in health requiring immediate treatment and advice.[21] Studies to date have demonstrated some clinical promise for the use of home telemonitoring in the context of heart failure and diabetes. A recent Cochrane review found that telemonitoring was an effective way to lower levels of glycated hemoglobin and low-density lipoprotein.[22] Although several studies on heart failure have produced conflicting results regarding the overall benefits of home monitoring,[23-26] systematic reviews have suggested that home telemonitoring reduces all-cause mortality and hospitalizations, and improves quality of life compared with usual care.[22,27] In addition, features such as automated and mobile telemonitoring appear to be more effective compared with other forms of home telemonitoring.[27]

Further studies are needed to determine how home health monitoring can improve patient safety during the transition from acute care to community care, and to examine the impact of home monitoring on health care costs. TEC4Home (Telehealth for Emergency-Community Continuity of Care Connectivity via Home Tele-monitoring), an initiative of the University of British Columbia and Vancouver Coastal Health, is seeking to do this with prospective trials designed to uncover how telemonitoring can support the safety of heart failure patients discharged from hospital to home.[28]

Mobile apps, wearables, and sensors in the clinical setting
Even though mobile apps, wearables, and sensor technologies are promising, further research is needed to validate their use and long-term impact.[29] This research will require the collaboration of clinicians, health researchers, engineers, and computer scientists.[30] Understanding the possible risks of using these technologies, from physiological harm to breaching of privacy and confidentiality with insecure devices, and how to mitigate any risks is also important. Other important issues to consider include patient anxiety with overuse of technologies, health data piracy, self-diagnosis resulting from overreliance on self-monitoring, and patients not seeking help appropriately. These technologies should be used only as complementary tools in the treatment and prevention of health conditions and disease and should not be used in isolation by patients who self-diagnose and self-manage without consulting a health professional. 

Kellogg/HKUST dominated this ranking from 2009 to 2014 but lost out to Trium in 2014 and to Tsinghua University/Insead in 2015.

Instant Heart Rate by Azumio.[31] A free app downloadable to both Apple and Android operating systems that measures heart rate and displays a monitoring strip. As well as helping users accurately track their heart rates, the app is capable of detecting irregular rhythms when palpitations occur. 

Sleep Time by Azumio.[32] A free app that monitors sleep patterns, sleep efficiency, and also acts as an alarm clock. Users can know how often they go into light and deep sleep, and recognize how much of these types of sleep will be necessary for them to feel rested, thereby quantifying the amount of true sleep they need and not just how long they should stay in bed. 

Bellybio Interactive Breating by RelaxLine.[33] A free app that helps users pace their breathing to achieve calmness. Placing the mobile phone against the abdomen, users can follow the sounds emitted to practise deep, abdominal breathing using this simple yet surprisingly effective tool. 

Some of the leaked photos and videos can still be found on Chinese social media as of press time.
?根据市长迈克尔?布隆伯格,报道的33个事故有10个发生在纽约,数字还有望上升。纽约的死亡是由于倒下的树木、电击和溺水。

王春法说,在出版前应加强审查和评估。
2013年日圆兑美元下跌21%,这为日本吸引来1,000万海外游客,尽管中日两国在东中国海(中国称东海)存在领土争端,然而这些游客中有许多是来自中国的富人。
2013年排名:3
The sketch of a monkey in an ink painting was made by Chinese contemporary artist Han Meilin, who also designed the "Fuwa" mascots for the 2008 Beijing Olympic Games. The ink painting was deemed "cute" by most web users, and represents a traditional art style. The program producer named the monkey "Kang Kang", which means "healthy" in Chinese.
The Peoria, Ill.-based maker of heavy equipment authorized $10 billion in stock repurchases in January and expected to buy back $1.7 billion of its shares in the first quarter this year to complete its previous $7.5 billion repurchase initiative. The ongoing buybacks are "a result of our record cash flow," said CEO Doug Oberhelman.
居民消费价格上涨2%;

Discernment to determine whether a particular app, wearable, or sensor can be effective.
Expertise and experience to guide patients on the use of technology.
Partnership with patients in pursuit of optimal health through technology use.
Trials to closely monitor benefits and drawbacks.
Humility to recognize that patients may know and invest much more time than physicians in looking for these tools.34

Conclusions
Based on today’s rapid pace of development and public enthusiasm for the technology marketplace, health apps, wearables, and sensors will soon become integral to our patients’ pursuits of good health and will need to be integrated in clinical practice. Physicians must be active agents in these evolutionary times, guiding patients, advocating for evidence to support the use of technologies, and participating in the development and incorporation of technology in patient wellness journeys. Through clinical stewardship and partnership with patients, physicians can use their expertise and experience to guide the growth of innovations into mainstream health care.

Competing interests
Dr Ho receives no personal financial compensation as the principal investigator of TEC4Home (Telehealth for Emergency-Community Continuity of Care Connectivity via Home Tele-monitoring), a project funded by a Canadian Institutes of Health Research grant. This grant is matched by the Michael Smith Foundation for Health Research and the BC Ministry of Health, with additional support provided by TELUS Health and Sentrian. TELUS Health, Cisco, and Avizia have also provided equipment for display in Dr Ho’s Demonstration and Simulation Studio for Health (DaSSH) at UBC. Mr Yao and Dr Lauscher have no competing interests to declare.


2018年交通运输固定资产投资约3.2万亿元 近四分之三投资用于公路水路


References

1. Cision PR Newswire. Fifth annual Pulse of Online Health survey finds 66% of Americans eager to leverage digital tools to manage personal health. Posted 24 February 2015. Accessed 28 August 2017. www.prnewswire.com/news-releases/fifth-annual-pulse-of-online-health-survey-finds-66-of-americans-eager-to-leverage-digital-tools-to-manage-personal-health-300039986.html.

2. Swan M. Emerging patient-driven health care models: An examination of health social networks, consumer personalized medicine and quantified self-tracking. Int J Environ Res Public Health 2009;6:492-525.

3. Gao Y, Li H, Luo Y. An empirical study of wearable technology acceptance in healthcare. Ind Manag Data Syst 2010;115:1704-1723.

4. Kim KJ, Shin DH. An acceptance model for smart watches: Implications for the adoption of future wearable technology. Internet Res 2015;25:527-541.

5. West JH, Hall PC, Hanson CL, et al. There’s an app for that: Content analysis of paid health and fitness apps. J Med Internet Res 2012;14:e72.

6. Abroms LC, Padmanabhan N, Thaweethai L, Phillips T. iPhone apps for smoking cessation: A content analysis. Am J Prev Med 2011;40:279-285.

7. Cowan LT, Van Wagenen SA, Brown BA, et al. Apps of steel: Are exercise apps providing consumers with realistic expectations? A content analysis of exercise apps for presence of behavior change theory. Health Educ Behav 2013;40:133-139.

8. Azar KM, Lesser LI, Laing BY, et al. Mobile applications for weight management. Am J Prev Med 2013;45:583-589.

9. Breland JY, Yeh VM, Yu J. Adherence to evidence-based guidelines among diabetes self-management apps. Transl Behav Med 2013;3:277-286.

10. Lyons EJ, Lewis ZH, Mayrsohn BG, Rowland JL. Behavior change techniques implemented in electronic lifestyle activity monitors: A systematic content analysis. J Med Internet Res 2014;16:e192.

11. Lewis ZH, Lyons EJ, Jarvis JM, Baillargeon J. Using an electronic activity monitor system as an intervention modality: A systematic review. BMC Public Health 2015;15:585.

12. Bort-Roig J, Gilson ND, Puig-Ribera A, et al. Measuring and influencing physical activity with smartphone technology: A systematic review. Sports Med 2014;44:671-686.

13. Rhodes RE, Yao CA. Models accounting for intention-behavior discordance in the physical activity domain: A user’s guide, content overview, and review of current evidence. Int J Behav Nutr Phys Act 2015;12:1-14.

14. Chen M, Gonzalez S, Vasilakos A, et al. Body area networks: A survey. Mob Networks Appl 2011;16:171-193.

15. Appelboom G, Camacho E, Abraham ME, et al. Smart wearable body sensors for patient self-assessment and monitoring. Arch Public Health 2014;72:28.

16. Chan M, Estève D, Fourniols JY, et al. Smart wearable systems: Current status and future challenges. Artif Intell Med 2012;56:137-156.

17. Alemdar H, Ersoy C. Wireless sensor networks for healthcare: A survey. Comput Networks 2010;54:2688-2710.

18. Haberman ZC, Jahn RT, Bose R, et al. Wireless smartphone ECG enables large-scale screening in diverse populations. J Cardiovasc Electrophysiol 2015;26:520-526.

19. Ferdman DJ, Liberman L, Silver ES. A smartphone application to diagnose the mechanism of pediatric supraventricular tachycardia. Pediatr Cardiol 2015;36:1452-1457.

20. Baquero GA, Banchs JE, Ahmed S, et al. Surface 12 lead electrocardiogram recordings using smart phone technology. J Electrocardiol 2015;48:1-7.

21. Wootton R. Twenty years of telemedicine in chronic disease management—An evidence synthesis. J Telemed Telecare 2012;18:211-220.

22. Flodgren G, Rachas A, Farmer A, et al. Interactive telemedicine: Effects on professional practice and health care outcomes. Cochrane Database System Rev 2015;(9):CD002098.

23. Mortara A, Pinna GD, Johnson P, et al. Home telemonitoring in heart failure patients: The HHH study (Home or Hospital in Heart Failure). Eur J Heart Fail 2009;11:312-318.

24. Dar O, Riley J, Chapman C, et al. A randomized trial of home telemonitoring in a typical elderly heart failure population in North West London: Results of the Home-HF study. Eur J Heart Fail 2009;11:319-325.

25. Chaudhry SI, Mattera JA, Curtis JP, et al. Telemonitoring in patients with heart failure. N Engl J Med 2010;363:2301-2309.

26. Koehler F, Winkler S, Schieber M, et al. Impact of remote telemedical management on mortality and hospitalizations in ambulatory patients with chronic heart failure: The Telemedical Interventional Monitoring in Heart Failure study. Circulation 2011;123:1873-1880.

27. Kitsiou S, Pare G, Jaana M. Effects of home telemonitoring interventions on patients with chronic heart failure: An overview of systematic reviews. J Med Internet Res 2015;17:e63.

28. TEC4Home Healthcare Innovation Community. Supporting heart failure patient transitions from acute to community care with home telemonitoring technology: A protocol for a provincial randomized controlled trial (TEC4Home). JMIR Res Protoc 2016;5:e198. 

29. Yao C, Ho K. Mobile sensors and wearable technologies. In: Amelung VE, Stein V, Goodwin N, et al., editors. Handbook integrated care. Cham, Switzerland: Springer; 2017.

30. Ho K, Borycki E, Kushniruk A, et al. The health perspective in using digital media for health and wellness. Presented at the IEEE International Digital Media Industry Forum, Boston, MA, 4-6 July 2016.

31. Azumio Inc. Instant heart rate. Accessed 28 August 2017. www.azumio.com/s/instantheartrate/index.html. 

32. Azumio Inc. Sleep time. Accessed 28 August 2017. www.azumio.com/s/sleeptime/index.html. 

33. RelaxLine. BellyBio. Accessed 28 August 2017. https://itunes.apple.com/ca/app/bellybio-interactive-breathing/id353763955?mt=8.

34. Ho K. How health information technologies are enhancing health of patients and their doctors. Presentation at the Alberta Medical Association 2015 Spring Representatives Forum, Edmonton, AB, 13 March 2015.


Frankly, this is unlikely to be ready in time for next year, but we'll include it just in case. The second film from Laszlo Nemes, who won the foreign language Oscar earlier this year for Son of Saul, is a coming-of-age drama set in Budapest just before the first world war.
When M·A·S·H first aired, the characters of Hawkeye and Trapper were meant to be equally sized roles. It was with that understanding that Wayne Rogers agreed to take the role of Trapper John. However, as Alan Alda began to make changes to the characters and have more influence on the direction of the show, Hawkeye began to seriously eclipse Trapper.
自高中以后,科比就没怎么变过,即便他已经离开劳尔梅里恩高中16年了。
碧昂斯与妮琪·米娜(Nicki Minaj),《完美》(Flawless, Remix),Parkwood/Columbia
马纳尔·阿尔-谢里夫最有名的,是挑战她的祖国压制女性的法律和习俗。
先是“非典”,接下来是全球范围的H5N1以及H1N1流感大爆发。全球化也无能为力。现在地球实际就是一个小村庄,这也使得病毒在几小时内,就能轻而易举地从北京传播到波士顿。2010我们是否会再次遭遇另一场“甲流”?
我们不希望通过贬值来增加出口,这不利于企业转型升级。
It was in Giambattista Valli’s most recent autumn-winter show, full of puffed-sleeve printed tunics over matching trousers and drop-waisted schoolgirls shifts, and in MaxMara’s ode to Marilyn Monroe’s 1962 photo shoot with George Barris.
根据考试结束后网上发布的考题和部分考生的反馈,今年的考题难度适中,长征火箭、我国外交事务、"玉兔"月球车和大学生创业等政治和社会热点问题都有出现。
The questions can seem like a sudden reversal after decades of rising multiculturalism, through the civil rights movement in the United States and the European Union’s opening up of borders.

Kendall Ho, MD, FRCPC, Christopher Yao, MSc, Helen Novak Lauscher, PhD. Part 2: Health apps, wearables, and sensors: The advancing frontier of digital health. BCMJ, Vol. 59, No. 10, December, 2017, Page(s) 503-506 - Clinical Articles.



Above is the information needed to cite this article in your paper or presentation. The International Committee of Medical Journal Editors (ICMJE) recommends the following citation style, which is the now nearly universally accepted citation style for scientific papers:
Halpern SD, Ubel PA, Caplan AL, Marion DW, Palmer AM, Schiding JK, et al. Solid-organ transplantation in HIV-infected patients. N Engl J Med. 2002;347:284-7.

About the ICMJE and citation styles

The ICMJE is small group of editors of general medical journals who first met informally in Vancouver, British Columbia, in 1978 to establish guidelines for the format of manuscripts submitted to their journals. The group became known as the Vancouver Group. Its requirements for manuscripts, including formats for bibliographic references developed by the U.S. National Library of Medicine (NLM), were first published in 1979. The Vancouver Group expanded and evolved into the International Committee of Medical Journal Editors (ICMJE), which meets annually. The ICMJE created the Tom Hanks has got a slightly more level head around his. He apparently keeps his best actor awards, one each for Philadelphia and Forrest Gump, on the family trophy shelf alongside football (the English kind) trophies and a World’s Greatest Mom trophy left from a mother’s day past. to help authors and editors create and distribute accurate, clear, easily accessible reports of biomedical studies.

Purchase products like magazine racks, shelves, and desk organizers that will keep your supplies and resources in order and close-at-hand. We love the File File, $24.95, at CB2.com (pictured above).
大宗农产品投机交易一直是今年市场波动的一个特点,荷兰合作银行预测,这种趋势将继续。
adj. 疲劳的
Of course, these same new forces may also trigger a backlash and a reversion to old command-and-control ways of leading. The politicians who dominate the world stage are, depressingly, mostly cut from the old cloth, and the leadership challenges they face, from Brexit to North Korea, are particularly complex.

vt. 谣传

  • Only the first three authors are listed, followed by "et al."
  • 个性化卫浴讲走红市场
  • 互联网风口下 家居电商的五大风向


和许多评论家一样,我一方面了解清单的便利,一方面也讨厌清单的专横。所以我永远不可能只列出十部――我怎么做得到呢,北美影院一年就要上映900多部影片呢――今年是2015年,所以我挑选了15部,为它们分门别类,计数时做了一点含糊,所以最后其实是20部。其中有两部片名的不代表并列,而是代表有两种特色,可以成对观看,二者的优点相映成趣。
The full list of this year's honorees follows.

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