Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
8.My resume is 5 pages long for a good reason. – Because I’m darn good at bullshittin’!
Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities
Soft matter science and the COVID-19 pandemic
The upcoming launch will mark the five-year anniversary of the sinking of a South Korean warship in 2010, with the loss of 46 sailors. The South pinned the blame on the North and effectively froze all inter-Korean trade and investment ties.
Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
*Guest Actor in a Drama Series: Hank Azaria, “Ray Donovan”
Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
还有仅仅9所商学院参与了所有4项排名。它们的排名从第三（西班牙企业商学院）到第38位（米兰理工大学MIP管理学院(Politecnico di Milano School of Management)）不等。
"Premier Wen Jiabao's speech had a big focus on economic and social development. It's clear the government is working very hard to bring about the goal of building a prosperous society."
Indeed, their ability to do so peacefully is among their strengths.
Trends and targets in antiviral phototherapy
PC demand has been hit by competition from smartphones and tablets, along with longer lifecycles for PCs. Shipments fell in all regions around the world and have declined for five quarters in a row, according to IDC's figures.
A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
Argentina, the host nation's big rivals, are in with a great chance too. Any team featuring Lionel Messi is going to be in with a shout, but when you add to that the likes of Sergio Aguero, Gonzalo Higuain and Ezequiel Lavezzi, then it's a team with one of the best sets of attacking options in the tournament. Likewise, Uruguay's attacking trio of Luis Suarez, Edinson Cavani and Diegoi Forlan is about as potent as it can get, and is capable of scoring goals against any team in the world, although whethere the rest of their team is strong enough is open to debate.
Novel biosensing methodologies for ultrasensitive detection of viruses
Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
ACE2 as a potential therapeutic target for pandemic COVID-19
Two days ago here in Brazil, we were shocked when we spent some time with some children living on the streets. And this is what one child told us: "I wish I was rich and if I were, I would give all the street children food, clothes, medicine, shelter and love and affection." 在巴西，我被2天前见到的情景震惊了，那时我和当地的小孩在玩耍，其中一个小孩说：“我希望我能富裕起来，然后我会给这个街道所有的小孩饭吃，给他们衣服穿，医疗，住房和爱”。
Diagnostic technologies for COVID-19: a review
NATO’s bombing campaign began on March 24 1999 after peace talks meant to stop the persecution of ethnic Albanians in Kosovo collapsed. Targets in both Yugoslavia and Kosovo were struck—first the Serb air defense network that opposed NATO planes then a broader target array including Yugoslav army forces said to be directly involved in the persecution of Kosovars. The target list also included political-military targets inside the Yugoslav capital of Belgrade itself.
Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
More importantly, their inventions may even eventually be turned into products that benefit mankind.
Dachis says: Kraft took a stance in support of genetically engineered foods midway through the year and the decision turned their brand into an overall loser for 2012.
随着新款iPhone不断刷新自己的发售纪录，库克推出了Apple Watch和Apple Pay等产品，引领苹果进入时尚界和金融界，让这家公司再度焕发出许多人担心已和乔布斯一同逝去的创新精神。苹果今年一年市值的增长，就接近谷歌(Google)的整体市值。
An overview of key potential therapeutic strategies for combat in the COVID-19 battle
Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
This year, several professions geared toward serving the financial and health needs of an aging population made the top ten, says Lee, including audiologist, financial planner, and physical therapist.
Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
Sam Smith is a fluid soul man, with style channeling Otis Redding, Aretha Franklin and Ray Charles alongside modern icons like Amy Winehouse and Adele.
In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
其他机构有宝钢集团(Shanghai Baosteel Group)旗下为钢材交易商提供融资的欧冶云商(Ouyeel)、中国第六大银行招商银行(China Merchants Bank)旗下专注财富管理领域的小企业e家(Small Entrepreneur)等。
Antiviral drug discovery: broad-spectrum drugs from nature
9. Putting Yourself in Someone Else's Shoes Improves Memory
In an interview with Yicai magazine last week, the chairman of China Construction Bank pointed to the rising tide of non-performing loans as the biggest problem confronting China’s banks.
Influenza neuraminidase: A druggable target for natural products
Honestly if you want to laugh your way through a Netflix original movie, please just watch The Incredible Jessica James because it's a delightful romantic comedy that blows everything else out of the water.
The attitude of the founder will set the tone for the business. Negativity, laziness and entitlement waste time and money while they tarnish your reputation. Success largely depends on making mistakes and accepting blame in stride. Owning up to and facing challenges head-on is what makes a mere business owner a leader.
Mr Koepke warns that this could easily be upset by the Fed.
Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
For as long as the show has been running — ever since its debut in 2007 — we have been, it seems, suffering from what Hadley Freeman in The Guardian newspaper dubbed “madmenalaria.”
The role of biosensors in the detection of emerging infectious diseases
“研究数据时，我不断回到这个问题上来，它其实是个身份政治问题，”挪威卑尔根大学(University of Bergen)研究欧洲极右翼党派的教授伊丽莎白?伊法斯夫拉腾(Elisabeth Ivarsflaten)说。“这是民粹主义者获得支持的最有力的征兆。”
Quantitative determination of mechanical stability in the novel coronavirus spike protein
Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
In the first 10 months of the year, Chinese exports to the US were up 5.2 per cent from the same period in 2014, while exports to countries in Asean were up 3.7 per cent, according to Chinese customs figures.
MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
So here are the main items to take into consideration if you’re trying to develop a business platform. These elements constitute will support a smart strategy for any new enterprise:
Harvard Business School, London Business School (LBS) and MIT Sloan School of Management, three of the MBA ranking’s longstanding heavyweights, all lost ground to their competitors. Harvard drops two places to fourth, the first time in nine years that the Boston school has been outside the top three. London Business School falls three places to sixth, its lowest position in 14 years. MIT Sloan School of Management falls to 13th place, the first time in 10 years that it has been outside the top 10.
Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
Effective bosses must be effective decision makers. He or she cannot vacillate over every tiny decision. Being able to make decisions quickly and decisively — and then take responsibility for the outcome (see number 2) — is an important business skill, especially when managing others。
She made several points in a note to clients Tuesday that struck me as new:
Inhibition of SARS coronavirus helicase by bismuth complexes
Over the three-year period we examined, late arrivals actually declined during the Thanksgiving travel season — just 12 percent of Thanksgiving flights were delayed last year, compared with 19 percent in 2010. according to the Transportation Department.
Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
Company: (Wonderbag) Natural Balance
A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
Historical and fictional films each have their own strengths when it comes to storytelling. Every now and then, though, movies pop up that don't quite fit into either category. The stories are wildly unrealistic, but they carry an inkling of truth between their pages. While these are some of the most interesting films out there, viewers often don't even know that what they're watching really happened. Well, wonder no more! Keep reading to learn about some of Hollywood's zanier scripts that took their inspiration from good old-fashioned real-life drama.
Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.
Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.
Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
It plans to help at least 130,000 rural people cast off poverty and relocate 163,000 residents in 2017.
A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring
Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
the truly embarrassing press conference from Vlade Divac, the leaks of Vivek Ranadive's lust for Buddy Hield, and the failure to sell off a host of spare veteran roster parts that theoretically could have been turned into picks.
4. Your co-worker blabbed。
The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
WORST USE OF SOCIAL MEDIA
Hillary stays on: Clinton’s CV is chock full of firsts: The only first lady to become a U.S. senator turned viable presidential candidate turned secretary of state. Now a private citizen, she continues to be one of the most watched and listened-to women on the planet. All bets on that she will be the 2016 Democratic presidential candidate and the free world’s presumptive next leader. She’s done little to quiet the chatter, including hitting the speaking circuit last month at an estimated $200,000 fee per event and inking a reported $14 million book deal.
Forget giving at least two weeks notice, finessing an exit interview, and tactfully networking your way out the door. Some people are in too big a hurry for any of that.
Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
6.Head-Mounted Computer Displays
Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
“The course was delivered by top-notch practitioners,” says one HEC Paris graduate. “The programme is perfectly designed for young professionals having limited finance experience and allows them to be immediately operational upon graduation.”
Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
201103/129769.shtmlEveryone tells a white lie on occasion, it’s just a question of why. Some white lies save relationships, some ease a hectic situation, and others buy us time. We all do it, so there is no reason to deny it. As long as we aren’t hurting others or breaking the law, these innocent lies can make life more pleasant. Most of these white lies only stretch aninterpretation of what the truth actually is anyways. Here’s a list of the 10most common white lies and why we tell them.
Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
“…said he never lets people see him sweat — but he was sweating profusely.”
2.The Tianjin Explosions
The Nobel Prize in physiology or medicine was awarded to a cellular-level experiment.
Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
Ironically the list comes out the same day that Trump is meeting with Bill Gates, who is the world's richest man for the fourth straight year.
The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
Indeed, their ability to do so peacefully is among their strengths.
Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
While Insead’s joint programme dropped back into second place, its single-school programme moved up three places to fourth, a place it last occupied in 2011.
Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.
Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.
Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.
Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
外部事件的影响。《消费者报告》（Consumer Reports）杂志曾经对Model S大加吹捧，但最近该杂志也报道了它的一些常见故障，包括门把手失效，中控触屏白屏，导致车内大部分功能不能使用等等。汽车网站Edmunds.com也找了Model S的麻烦。更多此类报告无疑会影响特斯拉到目前为止非常正面的声誉。
China has become the country with the most film screens in the world.
9. “The Big Short” Adam McKay plays it for comedy, but as he carpet-bombs the screen with laughs, he makes it clear that his take on the 2008 economic meltdown is a staggering American tragedy.
A modular microarray imaging system for highly specific COVID-19 antibody testing
Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.
Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
adj. 故意的，有意的；打算中的 n. 已订婚者 v.
A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
If you’re looking for a free CRM system, Zoho is probably the one for you. Why? It comes down to the integration possibilities. For example, Zoho integrates with JotForm and Unbounce simply by adding your API key. This means that within seconds, web leads will automatically be sent to your CRM. Pretty powerful for being free.
An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.
Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
“The steady and now record-breaking rise in average global temperatures is not an issue for another day,” Michael R. Bloomberg, the former New York mayor who is spending tens of millions of dollars of his personal fortune to battle climate change, said in a statement. “It’s a clear and present danger that poses major economic, health, environmental and geopolitical risks.”
A facile assay for rapid detection of COVID-19 antibodies
Here are the 10 bogies, drones targeting markets, stocks, bonds and the, global economy:
Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
While the S&P 500 is on track to conclude another stellar year of gains, those who sought to beat the index are poised to finish with a more dubious distinction. According to Lipper, 85% of all active stock mutual fund managers had been trailing their benchmarks through the end of November. In a typical year, there are nearly twice as many managers outperforming, with only around two thirds of funds struggling to catch up. Lipper says this is the worst year for active managers relative to the market in three decades.
Brazilian soccer fan Joedir Sancho Belmonte missed the 1950 World Cup final to stay home with his sick mother. Sixty-four years later, Belmonte exchanged his original unused ticket for three new tickets to the 2014 final.
Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
Yao has been at the center of a hostile takeover battle for China's largest real estate developer China Vanke Co Ltd (000002.SZ).
Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
13 Reasons Why
Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.
Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
Anti-HIV drug repurposing against SARS-CoV-2
迷你剧集/电影类最佳男演员：考特尼?B?万斯(Courtney B Vance)，《美国罪案故事：公诉辛普森》(The People v. O. J. Simpson: American Crime Story)
It is the eighth straight year that the metropolis has led Chinese cities in terms of consumer spending.
Length-scale dependence of protein hydration-shell density
4. 马克·特纳四重奏(Mark Turner Quartet)，《天堂里的车床》(Lathe of Heaven)， ECM。这是次中音萨克斯手马克·特纳13年来第一次以领队身份推出专辑，他喜欢同小号手阿维沙伊·科恩(Avishai Cohen)奏出流畅的互动，在后波普规范中发现全新意义。他的作曲中有纯粹的神秘，由乔伊·马丁(Joe Martin)担任贝斯手，马库斯·基尔默(Marcus Gilmore)担任鼓手的节奏组亦是一丝不苟。
High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
Apart from India, other BRICS nations -- Brazil, Russia, China and South Africa -- cut down their holdings of American government securities.
The main culprit for the deceleration was food, though food inflation is higher than the overall index. Food prices were up 1.9 per cent in October, down from 2.7 per cent in September and 3.7 per cent in August. Non-food inflation ticked down 0.9 per cent from 1.0 per cent.
A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
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